Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370735 | 0.74 | ALOX5 (0.60) | ALOX5MAOBADAM17 | |
| SCHEMBL9364971 | 0.72 | ALOX5 (0.63) | ALOX5MAOBADAM17 | |
| SCHEMBL9366371 | 0.71 | ALOX5 (0.58) | ALOX5MAOBADAM17 | |
| SCHEMBL9226309 | 0.71 | ALOX5 (0.60) | ALOX5ADAM17 | |
| SCHEMBL9365410 | 0.69 | ALOX5 (0.62) | ALOX5ADAM17 | |
| SCHEMBL9583379 | 0.69 | ALOX5 (0.62) | ALOX5ADAM17 | |
| SCHEMBL9365123 | 0.69 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9228038 | 0.69 | ALOX5 (0.49) | ALOX5ADAM17 | |
| SCHEMBL9366162 | 0.69 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9219840 | 0.69 | ALOX5 (0.63) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098932-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC, ICI PHARMA (FR) | 1992-03-24 | — | — | US | disclosed |