Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921825 | 0.78 | HDAC1 (0.58) | SLC29A1GRIN2BMEN1KMT2ANPSR1 | |
| SCHEMBL8917544 | 0.75 | HDAC1 (0.49) | SLC29A1GRIN2BHTR3EHTR3BHTR3A | |
| SCHEMBL8922623 | 0.74 | GRM5 (0.60) | GRIN2BMEN1KMT2ANPSR1CYP2C19 | |
| SCHEMBL6479590 | 0.73 | ALDH1A1 (0.63) | GRIN2BMEN1KMT2ANPSR1HDAC1 | |
| SCHEMBL8923780 | 0.72 | HDAC1 (0.52) | SLC29A1GRIN2BMEN1KMT2ANPSR1 | |
| SCHEMBL7658562 | 0.72 | L3MBTL1 (0.68) | MEN1KMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL4814264 | 0.71 | MEN1 (0.76) | GRIN2BMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL3970912 | 0.71 | MEN1 (0.76) | GRIN2BMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL379160 | 0.71 | MEN1 (0.76) | GRIN2BMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7393652 | 0.71 | MEN1 (0.76) | GRIN2BMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594702-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS. | UPJOHN CO (US) | 1994-05-04 | — | — | EP | disclosed |