Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371971 | 0.99 | HTR1A (0.58) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9369647 | 0.91 | KCNH2 (0.56) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9375609 | 0.90 | KCNH2 (0.54) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9375582 | 0.87 | HTR1A (0.58) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9372589 | 0.87 | HTR1A (0.69) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9372339 | 0.87 | HTR1A (0.55) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9373729 | 0.86 | DRD2 (0.44) | HTR1ADRD2HTR2A | |
| SCHEMBL9369887 | 0.86 | DRD2 (0.45) | HTR1ADRD2HTR2A | |
| SCHEMBL31013504 | 0.86 | HTR1A (0.71) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9370364 | 0.86 | HTR1A (0.71) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |