Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR7 | P34969 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369647 | 0.99 | KCNH2 (0.56) | KCNH2DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL9371971 | 0.90 | HTR1A (0.58) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9371995 | 0.90 | HTR1A (0.57) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9369094 | 0.89 | HTR1A (0.59) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9371917 | 0.88 | HTR1A (0.55) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9371795 | 0.87 | DRD2 (0.64) | KCNH2DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL9372762 | 0.86 | DRD3 (0.61) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9369887 | 0.85 | DRD2 (0.45) | DRD2HTR1AHTR2A | |
| SCHEMBL9373729 | 0.85 | DRD2 (0.44) | DRD2HTR1AHTR2A | |
| SCHEMBL9369082 | 0.83 | DRD2 (0.49) | DRD2HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5071845-A | Psychotropic or anxyiolytic agent | SUNTORY LIMITED (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |