⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380013 | 0.92 | — | — | |
| SCHEMBL9373128 | 0.89 | — | — | |
| SCHEMBL9373588 | 0.89 | — | — | |
| SCHEMBL9372406 | 0.86 | — | — | |
| SCHEMBL9488829 | 0.84 | MEN1 (0.40) | — | |
| SCHEMBL9378027 | 0.84 | MGLL (0.42) | — | |
| SCHEMBL9372039 | 0.84 | L3MBTL1 (0.41) | — | |
| SCHEMBL8532771 | 0.83 | — | — | |
| SCHEMBL8530545 | 0.83 | ALKBH2 (0.43) | — | |
| SCHEMBL14862819 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290145-B1 | Aliphatic carboxamides | ICI AMERICA INC (US) | 1994-10-26 | — | — | EP | disclosed |
| US-4894386-A | ANTIINFLAMMATORY AGENTS | ICI AMERICAS INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0290145-A1 | Aliphatic carboxamides | ZENECA INC. (US) | 1988-11-09 | — | — | EP | disclosed |