Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817854 | 0.73 | HTR2A (0.38) | ELANEMEN1KMT2AMAPT | |
| SCHEMBL37164 | 0.70 | — | — | |
| SCHEMBL4249639 | 0.70 | ELANE (0.36) | ELANENPSR1MAPTPOLBGAA | |
| SCHEMBL15763653 | 0.69 | ELANE (0.32) | ELANE | |
| SCHEMBL17193409 | 0.69 | ELANE (0.34) | ELANE | |
| SCHEMBL15757241 | 0.69 | ELANE (0.34) | ELANE | |
| SCHEMBL19531486 | 0.69 | ELANE (0.33) | ELANE | |
| SCHEMBL10326979 | 0.69 | ELANE (0.33) | ELANELMNA | |
| SCHEMBL9580536 | 0.67 | CRHR1 (0.33) | — | |
| SCHEMBL10327222 | 0.66 | EGFR (0.33) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2225459-A | — | — | None | — | — | JP | disclosed |
| EP-0377893-B1 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5186737-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5045560-A | Insecticides, nematocides, fungicides, herbicides, human and veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| JP-H02225459-A | PESTICIDAL TAUTOMER OF 3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVE | BAYER AG | 1990-09-07 | — | — | JP | disclosed |
| EP-0377893-A2 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1990-07-18 | — | — | EP | disclosed |