Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246772 | 0.73 | POLB (0.34) | ELANEMAPTNPSR1POLB | |
| SCHEMBL9372384 | 0.70 | ELANE (0.34) | ELANEMAPTNPSR1POLBGAA | |
| SCHEMBL17193409 | 0.65 | ELANE (0.34) | ELANE | |
| SCHEMBL20110944 | 0.64 | ELANE (0.43) | ELANEMAPTNPSR1CYP2C9 | |
| SCHEMBL15757241 | 0.63 | ELANE (0.34) | ELANE | |
| SCHEMBL10326979 | 0.63 | ELANE (0.33) | ELANE | |
| SCHEMBL12136938 | 0.63 | ELANE (0.33) | ELANEMAPT | |
| SCHEMBL19531486 | 0.63 | ELANE (0.33) | ELANE | |
| SCHEMBL17131539 | 0.62 | ELANE (0.43) | ELANEMAPT | |
| SCHEMBL13672448 | 0.61 | CNR1 (0.38) | ELANEMAPTHPGDNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
| EP-1771068-A1 | SUBSTITUTED 1H-PYRROLE-2,5-DIONES | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006007998-A1 | SUBSTITUTED 1H-PYRROLE-2,5-DIONES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | PYCR1, COX5A, COX5B | ELANE 3675/4885MAPT 2808/4885HPGD 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.