Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649692 | 0.70 | HTR2A (0.43) | CRHR1HTR2AHTR2CHTR2BAPAF1 | |
| SCHEMBL9372384 | 0.67 | ELANE (0.34) | — | |
| SCHEMBL9430112 | 0.62 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL4246772 | 0.62 | POLB (0.34) | CRHR1APAF1 | |
| SCHEMBL13139310 | 0.61 | HTR2A (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL25453060 | 0.61 | PARP1 (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL29209082 | 0.61 | BRD4 (0.42) | HTR2AHTR2CHTR2B | |
| SCHEMBL18560063 | 0.60 | KMT2A (0.40) | CRHR1 | |
| SCHEMBL25453054 | 0.58 | PARP1 (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL25453058 | 0.58 | PARP1 (0.37) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5262727-A | — | — | None | — | — | JP | disclosed |
| JP-H05262727-A | 4-(SUBSTITUTED)AMINO-3-ARYLPYRROLINONE DERIVATIVE | BAYER AG | 1993-10-12 | — | — | JP | disclosed |