Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372057 | 0.89 | CYP19A1 (0.49) | LMNACYP19A1CYP3A4CYP3A5SMN1; SMN2 | |
| SCHEMBL9372144 | 0.84 | NOTUM (0.46) | CYP19A1CYP3A4SMN1; SMN2KDM4EKCNA5 | |
| SCHEMBL9301221 | 0.81 | LMNA (0.46) | LMNACYP19A1CYP3A4CYP3A5SMN1; SMN2 | |
| SCHEMBL9375772 | 0.79 | POLB (0.41) | CYP19A1CYP3A4CYP3A5SMN1; SMN2KCNA5 | |
| SCHEMBL10730274 | 0.77 | CYP19A1 (0.44) | CYP19A1CYP3A4CYP3A5KCNA5 | |
| SCHEMBL12792525 | 0.76 | S1PR4 (0.40) | CYP19A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL10999210 | 0.75 | KCNA5 (0.47) | LMNACYP19A1CYP3A4KDM4EKCNA5 | |
| SCHEMBL12963162 | 0.73 | CYP19A1 (0.44) | LMNACYP19A1SMN1; SMN2KDM4E | |
| SCHEMBL12792714 | 0.72 | CYP19A1 (0.43) | LMNACYP19A1SMN1; SMN2KDM4E | |
| SCHEMBL933064 | 0.72 | CYP19A1 (0.43) | LMNACYP19A1CYP3A4CYP3A5KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438122-A | Combating fungi with 1-phenoxy-2-pyridinyl-alkanols | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | claimed |
| EP-0302366-B1 | Substituted pyridine derivatives | BAYER AG (DE) | 1994-09-14 | — | — | EP | disclosed |
| EP-0412820-B1 | 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-03-02 | — | — | EP | disclosed |
| US-5157038-A | Antidepressants; tranquilizers; treatment of schizophrenia and epilepsy; antilepmic agents | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-10-20 | — | — | US | disclosed |
| US-5047544-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-5036073-A | For agricultural use | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0412820-A2 | 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-13 | — | — | EP | disclosed |
| EP-0337229-A2 | Substituted pyri(mi)dines | BAYER AG (DE) | 1989-10-18 | — | — | EP | disclosed |
| EP-0302366-A2 | Substituted pyridine derivatives | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0302365-A2 | Substituted pyridines | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |