Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999210 | 0.80 | KCNA5 (0.47) | CYP3A4CYP19A1KCNA5 | |
| SCHEMBL933064 | 0.79 | CYP19A1 (0.43) | MAPTKMT2ACYP3A4CYP3A5CYP19A1 | |
| SCHEMBL9372769 | 0.79 | LMNA (0.48) | CYP3A4CYP3A5CYP19A1SMN1; SMN2KCNA5 | |
| SCHEMBL9372057 | 0.78 | CYP19A1 (0.49) | L3MBTL1KMT2ACYP3A4CYP3A5MEN1 | |
| SCHEMBL10516374 | 0.77 | CYP19A1 (0.43) | KMT2AMEN1CYP19A1SMN1; SMN2PDE2A | |
| SCHEMBL9372144 | 0.77 | NOTUM (0.46) | MAPTCYP3A4CYP19A1SMN1; SMN2KCNA5 | |
| SCHEMBL9373572 | 0.72 | CYP3A4 (0.50) | CYP3A4CYP3A5CYP19A1KCNA5 | |
| SCHEMBL9299239 | 0.70 | KCNA5 (0.49) | CYP3A4CYP3A5CYP19A1KCNA5 | |
| SCHEMBL10457874 | 0.70 | CYP19A1 (0.47) | KMT2ACYP3A4CYP3A5MEN1CYP19A1 | |
| SCHEMBL17171925 | 0.69 | CYP19A1 (0.39) | CYP3A4CYP3A5CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302366-B1 | Substituted pyridine derivatives | BAYER AG (DE) | 1994-09-14 | — | — | EP | disclosed |
| US-5047544-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-5036073-A | For agricultural use | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0302365-A2 | Substituted pyridines | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |