Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.46 |
| ▸ | HTR3B | O95264 | 4/20 | 0.46 |
| ▸ | HTR3A | P46098 | 4/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514390 | 0.85 | LMNA (0.44) | HTR2AHTTHTR6ALDH1A1 | |
| SCHEMBL2709917 | 0.85 | DRD2 (0.60) | DRD2DRD3ADRB1HTR3EHTR3B | |
| SCHEMBL16404650 | 0.83 | LMNA (0.43) | TP53THRBHTTALDH1A1 | |
| SCHEMBL2944271 | 0.81 | DRD2 (0.55) | DRD2DRD3ADRB1HTR3EHTR3B | |
| SCHEMBL4428637 | 0.81 | ADRB1 (0.65) | DRD2DRD3ADRB1HTR3EHTR3B | |
| SCHEMBL24990170 | 0.81 | ADRB1 (0.65) | DRD2DRD3ADRB1HTR3EHTR3B | |
| SCHEMBL3750968 | 0.81 | MAPT (0.63) | TP53CYP1A2THRBHTTALDH1A1 | |
| SCHEMBL18504221 | 0.81 | DRD2 (0.55) | DRD2DRD3ADRB1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL23302481 | 0.79 | DRD2 (0.54) | DRD2DRD3ADRB1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL29883021 | 0.79 | DRD2 (0.54) | DRD2DRD3ADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011596-A1 | AMIDE COMPOUND AND USE THEREOF | 中国药科大学 | 2023-02-09 | — | — | WO | disclosed |
| EP-0612313-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993010091-A2 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |