SCHEMBL9373385

SCHEMBL9373385

Nc1cc(OCC2CCCSC2)c(Cl)cc1F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 15/20 0.39
FFAR4 Q5NUL3 1/20 0.34
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9378276 0.87 SCN9A (0.40) SCN9A
SCHEMBL9873759 0.82 FFAR4 (0.44) SCN9AFFAR4
SCHEMBL9373987 0.80 DPP4 (0.39) SCN9AFFAR4
SCHEMBL27267930 0.77 SCN9A (0.46) SCN9AFFAR4
SCHEMBL30780907 0.77 SCN9A (0.46) SCN9AFFAR4
SCHEMBL30140248 0.73 SCN9A (0.41) SCN9AFFAR4
SCHEMBL9372659 0.73 SCN9A (0.35) SCN9A
SCHEMBL9641708 0.72 EPHA2 (0.34) SCN9AFFAR4HPGD
SCHEMBL9373884 0.72 PPOX (0.36) SCN9AHPGD
SCHEMBL10577542 0.70 NPC1 (0.34) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379099-B1 Tetrahydroindazoles with a phenyl ether structure BASF AG (DE) 1994-09-14 EP disclosed
US-5167690-A Pre- and postemergence RUEB LOTHAR (DE) 1992-12-01 US disclosed
US-5112383-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1992-05-12 US disclosed
US-4997472-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-03-05 US disclosed
EP-0379099-A1 Tetrahydroindazoles with a phenyl ether structure BASF Aktiengesellschaft (DE) 1990-07-25 EP disclosed