Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.65 |
| ▸ | FNTB | P49356 | 5/20 | 0.65 |
| ▸ | HRH1 | P35367 | 13/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | PTAFR | P25105 | 3/20 | 0.55 |
| ▸ | SLC6A15 | Q9H2J7 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373907 | 0.87 | PTAFR (0.74) | FNTAFNTBHRH1PTAFRSLC6A15 | |
| SCHEMBL14198336 | 0.86 | HRH1 (0.56) | FNTAFNTBHRH1CHRM2HTR1A | |
| SCHEMBL6994690 | 0.85 | HRH1 (0.71) | FNTAFNTBHRH1CHRM2HTR1A | |
| SCHEMBL9207250 | 0.84 | HRH1 (0.75) | FNTAFNTBHRH1KCNH2PTAFR | |
| SCHEMBL31384618 | 0.83 | HRH1 (0.82) | FNTAFNTBHRH1CHRM2HTR1A | |
| SCHEMBL4460572 | 0.83 | HRH1 (0.82) | FNTAFNTBHRH1CHRM2HTR1A | |
| SCHEMBL29626502 | 0.83 | HRH1 (0.82) | FNTAFNTBHRH1CHRM2HTR1A | |
| SCHEMBL6992437 | 0.83 | SLC6A15 (0.77) | FNTAFNTBHRH1CHRM2HTR2A | |
| SCHEMBL9387368 | 0.83 | FNTA (0.82) | FNTAFNTBHRH1PTAFRSLC6A15 | |
| SCHEMBL11576524 | 0.82 | SETD7 (0.56) | FNTAFNTBHRH1CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535152-B1 | Bis-benzo or benzopyrido cyclo hepta piperidene, piperidylene and piperazine compounds as PAF antagonists and compositions thereof. | SCHERING CORP (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5422351-A | Antiallergens; antiinflammatory agents | SCHERING CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0341860-B1 | Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use | SCHERING CORP (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0586560-A1 | NOVEL BENZOPYRIDO PIPERIDYLIDENE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020681-A1 | NOVEL BENZOPYRIDO PIPERIDYLIDENE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0515158-A1 | Novel benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use | SCHERING CORPORATION (US) | 1992-11-25 | — | — | EP | disclosed |
| US-5104876-A | Antiallergens, antiinflammatory agent | SCHERING CORPORATION | 1992-04-14 | — | — | US | disclosed |
| WO-1992000293-A1 | BIS-BENZO OR BENZOPYRIDO CYCLO HEPTA PIPERIDENE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1992-01-09 | — | — | WO | disclosed |
| EP-0341860-A1 | Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use | SCHERING CORPORATION (US) | 1989-11-15 | — | — | EP | disclosed |