Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856333 | 0.73 | TLR9 (0.52) | MGLLGPR84TLR9 | |
| SCHEMBL2362716 | 0.71 | MGLL (0.57) | MGLLHTR2ATLR9FAAH | |
| SCHEMBL7609673 | 0.70 | MGLL (0.70) | MGLLTLR9FAAH | |
| SCHEMBL29510492 | 0.69 | MGLL (1.00) | MGLLTLR9FAAH | |
| SCHEMBL3169850 | 0.69 | MGLL (1.00) | MGLLTLR9FAAH | |
| SCHEMBL10433672 | 0.68 | TSHR (0.48) | MGLLGPR84HTR2AHTR2CHTR2B | |
| SCHEMBL8316444 | 0.68 | GPR84 (0.47) | MGLLGPR84HTR2AFEN1FAAH | |
| SCHEMBL10433669 | 0.67 | MGLL (0.50) | MGLLTLR9HTR1AHTR7HTR6 | |
| SCHEMBL5691480 | 0.66 | MGLL (0.44) | MGLLGPR84HTR2ATLR9HTR2C | |
| SCHEMBL12120939 | 0.66 | GPR84 (0.58) | FFAR1GPR84HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630241-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |