Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374682 | 0.85 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2LMNAALOX15 | |
| SCHEMBL9374161 | 0.71 | ALOX15 (0.43) | MEN1KMT2ASMN1; SMN2LMNAALOX15 | |
| SCHEMBL9374671 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNA | |
| SCHEMBL13721336 | 0.69 | KDM4E (0.49) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL1787852 | 0.67 | HPGD (0.52) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL1791204 | 0.66 | NLRP3 (0.41) | SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL30814194 | 0.66 | NLRP3 (0.41) | SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL9530036 | 0.65 | POLB (0.67) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL30796577 | 0.65 | P2RX7 (0.51) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL1789170 | 0.65 | P2RX7 (0.51) | MEN1KMT2ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397350-B1 | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5182391-A | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1993-01-26 | — | — | US | disclosed |
| US-5171862-A | Process and indazole intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1992-12-15 | — | — | US | disclosed |
| US-5075442-A | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0397350-A1 | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4954629-A | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1990-09-04 | — | — | US | disclosed |