Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375560 | 0.89 | NISCH (0.61) | NISCH | |
| SCHEMBL9195272 | 0.74 | NISCH (0.53) | NISCH | |
| SCHEMBL1836133 | 0.74 | KDM4E (0.61) | NISCHACHE | |
| Bicarbonate SCHEMBL9412972 | 0.72 | NISCH (0.51) | NISCHACHE | |
| SCHEMBL14496851 | 0.72 | NISCH (0.62) | NISCH | |
| SCHEMBL7279147 | 0.71 | P4HA1 (0.58) | NISCH | |
| SCHEMBL548286 | 0.71 | NISCH (0.55) | NISCH | |
| Hydrochloric Acid SCHEMBL3900407 | 0.71 | NISCH (0.61) | NISCH | |
| SCHEMBL10473113 | 0.70 | NISCH (0.45) | NISCHACHE | |
| SCHEMBL11631248 | 0.70 | NISCH (0.41) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595015-A1 | Imidazolinyl-pyrimidines and their use as herbicides | BAYER AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| EP-0581086-A1 | Imidazolynyl-pyrimidines and their use as herbicides and fungicides | BAYER AG (DE) | 1994-02-02 | — | — | EP | disclosed |