Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371630 | 0.89 | RXFP1 (0.53) | MCL1PRSS12NPSR1RXFP1PRNP | |
| SCHEMBL1447569 | 0.84 | PRNP (0.60) | PRSS12NPSR1RXFP1PRNPTSHR | |
| SCHEMBL9372198 | 0.82 | EDNRA (0.61) | MCL1MAPTDYRK1AALDH1A1EDNRA | |
| SCHEMBL3050845 | 0.80 | HTT (0.46) | MCL1NPSR1RXFP1PRNPTSHR | |
| SCHEMBL5102909 | 0.78 | EDNRA (0.43) | RXFP1PRNPMAPTPTPN7DUSP3 | |
| SCHEMBL5211159 | 0.77 | NPSR1 (0.52) | MCL1PRSS12NPSR1RXFP1PRNP | |
| SCHEMBL1255148 | 0.76 | BCKDK (0.58) | MCL1RXFP1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL8877598 | 0.76 | MCL1 (0.56) | MCL1NPSR1RXFP1PRNPTSHR | |
| SCHEMBL64428 | 0.75 | MCL1 (0.73) | MCL1RXFP1PRNPHTTMAPT | |
| SCHEMBL3155578 | 0.75 | LTA4H (0.50) | TSHRHTTMAPTSMN1; SMN2PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299457-B1 | Novel benzothiophenes having antiallergic activity and both novel and other selected benzothiophenes having activity for treating acute respiratory distress syndrome | WARNER LAMBERT CO (US) | 1994-09-21 | — | — | EP | disclosed |
| US-4931459-A | ADMINISTERING SUBSTITUTED BENZOTHIOPHENES OR BENZOFURANS | WARNER-LAMBERT COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| US-4910317-A | Containing a 5-amidetetrazole substitution in position 2 | WARNER-LAMBERT COMPANY (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0299457-A2 | Novel benzothiophenes having antiallergic activity and both novel and other selected benzothiophenes having activity for treating acute respiratory distress syndrome | WARNER-LAMBERT COMPANY (US) | 1989-01-18 | — | — | EP | disclosed |