Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | BRD4 | O60885 | 4/20 | 0.68 |
| ▸ | BRD2 | P25440 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18660612 | 0.89 | HTT (0.80) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6972083 | 0.88 | HTT (0.79) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19260255 | 0.85 | HTT (0.74) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6962591 | 0.84 | HTT (0.71) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9381334 | 0.83 | HTT (0.71) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2798583 | 0.82 | HTT (0.69) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29897959 | 0.82 | HTT (0.69) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31140232 | 0.82 | HTT (0.69) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27180011 | 0.81 | HTT (0.66) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30788269 | 0.81 | HTT (0.66) | HTTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590022-A1 | IMIDAZO 1,5-a]QUINOXALINES | PHARMACIA & UPJOHN COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |