Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BRD2 | P25440 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964190 | 0.88 | BRD4 (0.60) | HTTALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL9375233 | 0.84 | HTT (1.00) | HTTALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL6972083 | 0.82 | HTT (0.79) | HTTALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL6958783 | 0.80 | L3MBTL1 (0.54) | HTTALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6972803 | 0.80 | L3MBTL1 (0.69) | HTTALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL6964138 | 0.80 | L3MBTL1 (0.60) | HTTALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6971322 | 0.79 | ALDH1A1 (0.60) | HTTALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL3044124 | 0.76 | KCNN4 (0.68) | HTTALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL30788269 | 0.75 | HTT (0.66) | HTTALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL27180011 | 0.75 | HTT (0.66) | HTTALDH1A1NPSR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |