Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | BRD4 | O60885 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BRD2 | P25440 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375233 | 0.88 | HTT (1.00) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL6966461 | 0.86 | BRD4 (0.65) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL6962591 | 0.82 | HTT (0.71) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL19960683 | 0.79 | HTT (0.68) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL18660612 | 0.78 | HTT (0.80) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL6965999 | 0.77 | LMNA (0.57) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL2798583 | 0.77 | HTT (0.69) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL19260255 | 0.77 | HTT (0.74) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL29897959 | 0.77 | HTT (0.69) | HTTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL25430532 | 0.77 | CASP3 (0.76) | HTTALDH1A1LMNANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |