Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 4/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371852 | 0.81 | SCN8A (0.33) | ABCC9ABCB1MAOBMALT1PDE4A | |
| SCHEMBL10435559 | 0.80 | SMN1; SMN2 (0.35) | ABCC9ABCB1CASP3BACE1CTSD | |
| SCHEMBL9373913 | 0.77 | ABCC9 (0.33) | ABCC9ABCB1MAOBMALT1BACE1 | |
| SCHEMBL9779813 | 0.75 | ALK (0.38) | ABCC9ABCB1MAOBMALT1BACE1 | |
| SCHEMBL9375455 | 0.74 | PDE4A (0.33) | ABCC9MALT1PDE4APDE4BPDE4C | |
| SCHEMBL9376866 | 0.73 | PDPK1 (0.34) | ABCC9ABCB1 | |
| SCHEMBL9372537 | 0.73 | ABCC9 (0.34) | ABCC9ABCB1 | |
| SCHEMBL9371377 | 0.72 | ABCC9 (0.32) | ABCC9 | |
| SCHEMBL9779754 | 0.72 | ABCC9 (0.38) | ABCC9 | |
| SCHEMBL9371892 | 0.72 | ABCC9 (0.32) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371312-B1 | Benzoxazine derivatives | MERCK PATENT GMBH (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5036068-A | Cardiovascular disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0371312-A1 | Benzoxazine derivatives | MERCK PATENT GmbH (DE) | 1990-06-06 | — | — | EP | disclosed |