Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.59 |
| ▸ | RAB9A | P51151 | 14/20 | 0.59 |
| ▸ | PKM | P14618 | 6/20 | 0.59 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | SCD | O00767 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963858 | 0.78 | RAB9A (0.76) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL11703736 | 0.78 | NPC1 (0.91) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9374793 | 0.78 | CYP26A1 (0.53) | MEN1KMT2APOLB | |
| SCHEMBL9376520 | 0.77 | TOP1 (0.58) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11703862 | 0.77 | NPC1 (0.83) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9377709 | 0.77 | HTT (0.50) | NPC1RAB9AOPRK1SMN1; SMN2MEN1 | |
| SCHEMBL2957526 | 0.77 | NPC1 (0.68) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL11705464 | 0.76 | RAB9A (0.72) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9834995 | 0.76 | PDE4A (0.55) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL10558334 | 0.76 | RAB9A (0.58) | NPC1RAB9APKMKLF5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |
| CN-1038640-A | Two ring carboxamide, its preparation methods and contain the pharmaceutical composition of this material | BOEHRINGER MANNHEIM GMBH (DE) | 1990-01-10 | — | — | CN | disclosed |
| EP-0344634-A1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | disclosed |