Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881270 | 0.75 | HRH3 (0.39) | ACE2KDM1ASMN1; SMN2 | |
| SCHEMBL248151 | 0.72 | KEAP1 (0.56) | ACE2SMN1; SMN2KEAP1PAOXALOX15 | |
| SCHEMBL10289067 | 0.71 | TP53 (0.44) | USP2SMN1; SMN2TP53PAOXKMT2A | |
| Hydrochloric Acid SCHEMBL7427988 | 0.70 | KEAP1 (0.54) | ACE2SMN1; SMN2KEAP1PAOXALOX15 | |
| SCHEMBL856408 | 0.70 | SIGMAR1 (0.50) | ACE2SMN1; SMN2KEAP1PAOXALOX15 | |
| Hydrochloric Acid SCHEMBL3677133 | 0.68 | SIGMAR1 (0.48) | SMN1; SMN2KEAP1PAOXALOX15SIGMAR1 | |
| SCHEMBL31092072 | 0.68 | PAOX (0.53) | SMN1; SMN2KEAP1PAOXALOX15SIGMAR1 | |
| SCHEMBL3970460 | 0.68 | PAOX (0.53) | SMN1; SMN2KEAP1PAOXALOX15SIGMAR1 | |
| SCHEMBL22564678 | 0.68 | PAOX (0.53) | SMN1; SMN2KEAP1PAOXALOX15SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27751183 | 0.68 | SIGMAR1 (0.48) | SMN1; SMN2KEAP1PAOXALOX15SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614664-A1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |