SCHEMBL9376282

SCHEMBL9376282

CNc1cccc(S(N)(=O)=O)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.42
SCN5A Q14524 1/20 0.42
HSD11B1 P28845 1/20 0.39
CA1 P00915 7/20 0.38
CA2 P00918 7/20 0.38
CA12 O43570 3/20 0.38
NCF1 P14598 1/20 0.38
CA9 Q16790 5/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA7 P43166 2/20 0.38
CA13 Q8N1Q1 2/20 0.38
CA14 Q9ULX7 2/20 0.38
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 1/20 0.36
ALOX15 P16050 1/20 0.36
SCN10A Q9Y5Y9 1/20 0.36
HTR6 P50406 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29051854 0.81 KCNH2 (0.42) KCNH2SCN5AHSD11B1NCF1ALDH1A1
SCHEMBL22982222 0.77 MAPT (0.60) CA1CA2CA12CA9CA6
SCHEMBL22116391 0.77 CASR (0.47) CA1CA2SCN10ACASRKDM4E
SCHEMBL29862331 0.77 MAPT (0.60) CA1CA2CA12CA9CA6
SCHEMBL6449500 0.74 SLC40A1 (0.47) HSD11B1CA1CA2CA12CA9
SCHEMBL318096 0.73 KCNH2 (0.57) KCNH2SCN5AHSD11B1NCF1CYP3A4
SCHEMBL3465415 0.73 CA2 (0.34) CA1CA2CA12CA9CA4
SCHEMBL24234002 0.72 CA1 (0.46) CA1CA2CA12CA9CA7
SCHEMBL17647899 0.71 NOS3 (0.43) CA1CA2CA12NCF1CA9
SCHEMBL6501463 0.69 CYP3A4 (0.43) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233863-A1 ENPP1 INHIBITORS RE VENTURES I, LLC (US) 2025-11-13 WO disclosed
WO-2021030556-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2021-02-18 WO disclosed
EP-0314505-B1 Herbicidal pyridine sulfonylureas DU PONT (US) 1994-02-16 EP disclosed
US-5032166-A Pre and postemergent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-16 US disclosed
US-4946494-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-07 US disclosed
EP-0314505-A2 Herbicidal pyridine sulfonylureas E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-03 EP disclosed