Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372322 | 0.92 | HTT (0.40) | HTTALDH1A1SMN1; SMN2MAPK14NPSR1 | |
| SCHEMBL9372323 | 0.88 | NPBWR1 (0.41) | HTTALDH1A1SMN1; SMN2MAPK14NPSR1 | |
| SCHEMBL5621937 | 0.84 | MAPK14 (0.36) | HTTALDH1A1SMN1; SMN2MAPK14NPSR1 | |
| SCHEMBL92683 | 0.80 | MAPK14 (0.37) | HTTALDH1A1SMN1; SMN2MAPK14NPSR1 | |
| SCHEMBL9373345 | 0.77 | MAPK14 (0.38) | APPHTTALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL9239763 | 0.75 | RAB9A (0.43) | APPHTTALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL9372983 | 0.74 | HTT (0.54) | HTTALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL18672244 | 0.73 | HTT (0.37) | HTTALDH1A1SMN1; SMN2MAPK14NPSR1 | |
| SCHEMBL19313567 | 0.72 | HTT (0.39) | HTTALDH1A1SMN1; SMN2MAPK14NPSR1 | |
| SCHEMBL31130800 | 0.72 | MAPK14 (0.36) | HTTALDH1A1SMN1; SMN2MAPK14NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302346-B1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-4945091-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-31 | — | — | US | disclosed |
| EP-0302346-A2 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |