Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378088 | 0.78 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL6580747 | 0.75 | GAA (0.50) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL6218416 | 0.75 | GAA (0.50) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL9380281 | 0.74 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL1487109 | 0.73 | PABPC1 (0.53) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL714617 | 0.73 | PABPC1 (0.53) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL8625830 | 0.73 | PABPC1 (0.53) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL8192982 | 0.73 | PABPC1 (0.53) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL8200760 | 0.73 | PABPC1 (0.53) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL9739360 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562042-A4 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0562042-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5137892-A | Bactericides | ABBOTT LABORATORIES (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | disclosed |