Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384132 | 0.81 | HTR1A (0.31) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8325616 | 0.80 | PABPC1 (0.53) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL9524924 | 0.77 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL9738016 | 0.76 | HTR1A (0.31) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL5163226 | 0.76 | PABPC1 (0.35) | HTR1APABPC1CTDSP1GAA | |
| SCHEMBL9377673 | 0.74 | HTR1A (0.36) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL13661568 | 0.73 | GAA (0.61) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL9736937 | 0.72 | — | — | |
| SCHEMBL8878463 | 0.72 | PABPC1 (0.36) | PABPC1CTDSP1GAA | |
| SCHEMBL1768148 | 0.69 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562042-A4 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | disclosed |