Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679282 | 0.71 | TAAR1 (0.64) | TAAR1HTR1AALOX15ALDH1A1TBXAS1 | |
| SCHEMBL10927112 | 0.68 | PDE3B (0.52) | TAAR1MAPTKMT2A | |
| SCHEMBL4462633 | 0.67 | AXL (0.50) | TAAR1GAAALDH1A1MAPTADRA2A | |
| SCHEMBL6091136 | 0.64 | ESR1 (0.43) | GAAALDH1A1MAPTKMT2A | |
| SCHEMBL13372830 | 0.64 | TAAR1 (0.80) | TAAR1HTR1AALOX15ALDH1A1ADRA2A | |
| SCHEMBL1659954 | 0.64 | — | — | |
| SCHEMBL3431563 | 0.63 | — | — | |
| SCHEMBL262513 | 0.63 | — | — | |
| SCHEMBL6448262 | 0.62 | TBXAS1 (0.59) | TAAR1HTR1AALOX15GAATBXAS1 | |
| SCHEMBL285224 | 0.62 | TERT (0.59) | TAAR1HTR1AALOX15ALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269030-B1 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5089515-A | Antiischemic agents; pyrazolone compounds | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4990619-A | Cardiovascular disorders, antiischemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4906644-A | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0269030-A2 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-01 | — | — | EP | disclosed |