Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795369 | 0.91 | HTR2A (0.44) | HTR1ADRD2HTR2A | |
| SCHEMBL373467 | 0.90 | BCHE (0.44) | HTR1ADRD2HTR2ABCHEACHE | |
| Hydrochloric Acid SCHEMBL1545403 | 0.89 | BCHE (0.43) | HTR1ADRD2HTR2ABCHEACHE | |
| SCHEMBL5995383 | 0.89 | BCHE (0.43) | HTR1ADRD2HTR2ABCHEACHE | |
| SCHEMBL23175425 | 0.81 | DRD2 (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL7356803 | 0.80 | ACHE (0.55) | DRD2HTR2AACHE | |
| SCHEMBL7726651 | 0.79 | ACHE (0.55) | DRD2HTR2AACHE | |
| Hydrochloric Acid SCHEMBL1544936 | 0.79 | ACHE (0.54) | DRD2HTR2AACHE | |
| SCHEMBL7966226 | 0.78 | DRD2 (0.39) | HTR1ADRD2HTR2A | |
| SCHEMBL7966228 | 0.78 | DRD2 (0.39) | HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428437-B1 | 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-08-17 | — | — | EP | disclosed |
| US-5134147-A | Antipsychotic agents | ADIR ET COMPAGNIE (FR) | 1992-07-28 | — | — | US | disclosed |
| EP-0428437-A1 | 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-05-22 | — | — | EP | disclosed |