Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 8/20 | 0.42 |
| ▸ | HTR2A | P28223 | 8/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995383 | 0.98 | BCHE (0.43) | BCHEACHESLC18A3SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL1545403 | 0.98 | BCHE (0.43) | BCHEACHESLC18A3SIGMAR1HTR1A | |
| SCHEMBL9377809 | 0.90 | HTR1A (0.39) | BCHEACHEHTR1ADRD2HTR2A | |
| SCHEMBL7726651 | 0.88 | ACHE (0.55) | ACHEDRD2HTR2AHTR2C | |
| SCHEMBL23175425 | 0.88 | DRD2 (0.46) | HTR1ADRD2HTR2A | |
| SCHEMBL12026856 | 0.83 | HIF1A (0.49) | ACHEHTR1ADRD2HTR2A | |
| SCHEMBL795369 | 0.81 | HTR2A (0.44) | HTR1ADRD2HTR2AHTR2C | |
| SCHEMBL3263185 | 0.81 | DRD2 (0.44) | HTR1ADRD2HTR2A | |
| SCHEMBL7966226 | 0.80 | DRD2 (0.39) | HTR1ADRD2HTR2A | |
| SCHEMBL7966228 | 0.80 | DRD2 (0.39) | HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796090-B | Method for preparing iloperidone | TIANJIN HUAJIN PHARMACEUTICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-102070626-A | Novel method for preparing iloperidone | HAINAN KANGHONG PHARMACEUTICAL R & D CO LTD | 2011-05-25 | — | — | CN | claimed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | claimed |
| US-5385916-A | 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents | PFIZER INC. (US) | 1995-01-31 | — | — | US | claimed |
| EP-0557289-B1 | 4-(1,2-BENZISOXAZOLYL)PIPERIDINE ANTIPSYCHOTIC AGENTS | PFIZER (US) | 1994-12-28 | — | — | EP | claimed |
| US-5276040-A | 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents | PFIZER INC. (US) | 1994-01-04 | — | — | US | claimed |
| US-5147881-A | 4-(1,2-BENZISOXAZOLYL)PIPERIDINE ANTIPSYCHOTIC AGENTS | PFIZER INC (US) | 1992-09-15 | — | — | US | claimed |
| WO-1992008718-A1 | 4-(1,2-BENZISOXAZOLYL)PIPERIDINE ANTIPSYCHOTIC AGENTS | PFIZER INC. (US) | 1992-05-29 | — | — | WO | claimed |
| EP-0080104-B1 | 3-(4-PIPERIDYL)-1,2-BENZISOXAZOLES, PROCESS FOR THE PREPARATION THEREOF, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-12-14 | — | — | EP | claimed |
| EP-0080104-A2 | 3-(4-Piperidyl)-1,2-benzisoxazoles, process for the preparation thereof, and a pharmaceutical composition comprising the same | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-06-01 | — | — | EP | claimed |
| US-4355037-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS (US) | 1982-10-19 | — | — | US | claimed |
| JP-10059967-A | — | — | None | — | — | JP | disclosed |
| JP-58090582-A | — | — | None | — | — | JP | disclosed |
| US-20260078115-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2026-03-19 | — | — | US | disclosed |
| US-12503463-B2 | Aliphatic acid amide derivative | Sumitomo Pharma Co., Ltd. (JP) | 2025-12-23 | — | — | US | disclosed |
| JP-S5890582-A | 3-(4-PIPERIDYL)-1,2-BENZISOXAZOLE COMPOUND | HOECHST ROUSSEL PHARMA | 1983-05-30 | — | — | JP | disclosed |
| EP-0079564-A1 | 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles, a process for the preparation thereof, a pharmaceutical composition comprising the same, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-05-25 | — | — | EP | disclosed |
| US-4355037-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS (US) | 1982-10-19 | — | — | US | disclosed |
| US-4355037-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS (US) | 1982-10-19 | — | — | US | disclosed |
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503463-B2 | Aliphatic acid amide derivative | HTR2A, HTR1A, HTR7 | BCHE 3307/4885ACHE 1920/4885SLC18A3 593/4885 |
| US-20260078115-A1 | ALIPHATIC ACID AMIDE DERIVATIVE | HTR1D, HTR1A, HTR7 | BCHE 2651/4885ACHE 2428/4885SLC18A3 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.