Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.51 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378886 | 0.90 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL9378248 | 0.90 | LOX (0.50) | CYP19A1CYP11B1CYP11B2LOXLOXL3 | |
| SCHEMBL9383847 | 0.89 | CYP11B1 (0.45) | CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL9378661 | 0.88 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2ATM | |
| SCHEMBL9378673 | 0.85 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2QPCTATM | |
| SCHEMBL9377424 | 0.85 | TBXAS1 (0.42) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9383432 | 0.84 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2QPCTATM | |
| SCHEMBL9382448 | 0.81 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL9383526 | 0.76 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9378296 | 0.75 | CES2 (0.55) | CYP19A1CYP11B1CYP11B2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269030-B1 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5089515-A | Antiischemic agents; pyrazolone compounds | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4990619-A | Cardiovascular disorders, antiischemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4906644-A | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0269030-A2 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-01 | — | — | EP | disclosed |