Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 12/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378673 | 0.90 | CYP19A1 (0.49) | CES2CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL9380107 | 0.89 | CES2 (0.46) | CES2CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9383526 | 0.88 | CYP19A1 (0.48) | CES2CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL9381460 | 0.87 | CYP19A1 (0.47) | CES2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9379264 | 0.86 | CYP11B1 (0.40) | CES2CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9378248 | 0.85 | LOX (0.50) | CES2CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9380139 | 0.84 | TBXAS1 (0.41) | CES2CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL9379529 | 0.83 | SIGMAR1 (0.40) | CES2CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL9378706 | 0.82 | CYP11B1 (0.43) | CES2CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9382448 | 0.79 | CYP19A1 (0.45) | CES2CYP19A1CYP11B1CYP11B2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269030-B1 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5089515-A | Antiischemic agents; pyrazolone compounds | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4906644-A | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0269030-A2 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-01 | — | — | EP | disclosed |