Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379529 | 0.90 | SIGMAR1 (0.40) | SIGMAR1ALOX15HSD17B10CYP19A1CYP11B1 | |
| SCHEMBL9382915 | 0.89 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP17A1CYP21A2CYP11B2 | |
| SCHEMBL9382448 | 0.86 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9380107 | 0.84 | CES2 (0.46) | CYP19A1LMNACYP11B1CYP17A1CYP11B2 | |
| SCHEMBL9378469 | 0.84 | CYP11B1 (0.46) | HSD17B10CYP19A1LMNASMN1; SMN2CYP11B1 | |
| SCHEMBL9379946 | 0.84 | TBXAS1 (0.41) | CYP19A1LMNASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9379777 | 0.83 | CYP19A1 (0.43) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9383381 | 0.78 | CYP11B1 (0.36) | CYP19A1LMNASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9383526 | 0.78 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP17A1CYP21A2CYP11B2 | |
| SCHEMBL9380139 | 0.76 | TBXAS1 (0.41) | CYP19A1LMNASMN1; SMN2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269030-B1 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5089515-A | Antiischemic agents; pyrazolone compounds | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4990619-A | Cardiovascular disorders, antiischemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4906644-A | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0269030-A2 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-01 | — | — | EP | disclosed |