Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565494 | 0.73 | GBA1 (0.45) | GBA1POLBCCR3CALM1 | |
| SCHEMBL6519938 | 0.71 | GBA1 (0.43) | GBA1POLBCCR3CALM1 | |
| SCHEMBL1930265 | 0.70 | GBA1 (0.47) | GBA1POLBCCR3 | |
| SCHEMBL1200483 | 0.70 | GBA1 (0.42) | GBA1POLBCCR3CALM1 | |
| SCHEMBL9700293 | 0.67 | ALDH1A1 (0.37) | GBA1CALM1 | |
| SCHEMBL2027845 | 0.65 | GBA1 (0.71) | GBA1CCR3 | |
| SCHEMBL19809006 | 0.65 | CALM1 (0.43) | GBA1CALM1 | |
| SCHEMBL674276 | 0.65 | GBA1 (0.71) | GBA1CCR3 | |
| SCHEMBL1200566 | 0.65 | GBA1 (0.42) | GBA1POLBCCR3 | |
| SCHEMBL1929149 | 0.65 | POLB (0.43) | GBA1POLBCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428437-B1 | 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-08-17 | — | — | EP | disclosed |
| EP-0428437-A1 | 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-05-22 | — | — | EP | disclosed |