Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68066 | 0.87 | VHL (0.50) | PGRMEN1KMT2AMAPK13DAPK3 | |
| SCHEMBL1987343 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL31260278 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL31260280 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL15497458 | 0.76 | KDM4E (0.35) | MAPTKDM4EALDH1A1MAOBHPGD | |
| SCHEMBL6592274 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL13339955 | 0.74 | PPOX (0.37) | PGRMEN1KMT2AMAPK13DAPK3 | |
| SCHEMBL9161289 | 0.74 | CES1 (0.42) | MEN1KMT2AMAPK13DAPK3ROCK2 | |
| Hydrochloric Acid SCHEMBL3493932 | 0.73 | PPOX (0.36) | PGRMEN1KMT2AMAPK13DAPK3 | |
| SCHEMBL68563 | 0.71 | KDM4E (0.48) | PGRMEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286346-B1 | Insecticidal substituted indazoles | DU PONT (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0438458-A1 | SUBSTITUTED INDAZOLES AS ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4960784-A | Insecticidal substituted indazoles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0365201-A1 | Substituted indazoles as arthropodicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1990003969-A1 | SUBSTITUTED INDAZOLES AS ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-19 | — | — | WO | disclosed |
| EP-0362216-A1 | INSECTICIDAL SUBSTITUTED INDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988007994-A1 | INSECTICIDAL SUBSTITUTED INDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-20 | — | — | WO | disclosed |
| EP-0286346-A2 | Insecticidal substituted indazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-12 | — | — | EP | disclosed |