Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375313 | 0.73 | ALDH1A1 (0.47) | TDP1ALDH1A1OPRM1OPRL1MAPT | |
| SCHEMBL11574696 | 0.70 | TP53 (0.33) | POLBL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL464733 | 0.67 | EGFR (0.36) | MAPT | |
| SCHEMBL30350644 | 0.67 | FFAR4 (0.44) | PKMALDH1A1MAPT | |
| SCHEMBL12036060 | 0.67 | FFAR4 (0.44) | PKMALDH1A1MAPT | |
| SCHEMBL2259304 | 0.65 | PGR (0.59) | MAPT | |
| SCHEMBL8881506 | 0.63 | MOGAT2 (0.46) | MOGAT2MAPT | |
| Hydrochloric Acid SCHEMBL8493528 | 0.63 | PGR (0.57) | MAPT | |
| SCHEMBL25313851 | 0.62 | CYP1A2 (0.53) | POLBMAPT | |
| SCHEMBL30132814 | 0.62 | CYP1A2 (0.53) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590022-A1 | IMIDAZO 1,5-a]QUINOXALINES | PHARMACIA & UPJOHN COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |