Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OGT | O15294 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 5/20 | 0.35 |
| ▸ | NOS2 | P35228 | 4/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468841 | 1.00 | KMO (0.37) | KMOKDM4EOGTNOS1NOS2 | |
| SCHEMBL9380892 | 0.82 | NOS1 (0.42) | KMOKDM4EOGTNOS1NOS2 | |
| SCHEMBL24207806 | 0.81 | KMO (0.35) | KMOKDM4EOGTNOS1NOS2 | |
| SCHEMBL8873741 | 0.81 | KDM4E (0.41) | KDM4EMAPTDAOTGM2 | |
| SCHEMBL5543668 | 0.81 | KMO (0.35) | KMOOGTNOS1NOS2NOS3 | |
| SCHEMBL30444318 | 0.81 | KMO (0.35) | KMOOGTNOS1NOS2NOS3 | |
| SCHEMBL18062718 | 0.81 | KMO (0.35) | KMOOGTNOS1NOS2NOS3 | |
| SCHEMBL5543671 | 0.81 | NOS1 (0.49) | KMOOGTNOS1NOS2NOS3 | |
| SCHEMBL2150170 | 0.81 | KMO (0.35) | KMOOGTNOS1NOS2NOS3 | |
| SCHEMBL24512761 | 0.75 | CREBBP (0.34) | KMOKDM4EOGTNOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912601-B | Novel imidazo [1,2-a ] pyridine derivatives, preparation method and medical application thereof | 上海拓界生物医药科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-113912601-A | Novel imidazo [1,2-a ] pyridine derivatives, preparation method and medical application thereof | 上海拓界生物医药科技有限公司 | 2022-01-11 | — | — | CN | disclosed |
| EP-0409484-B1 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5071863-A | Antiallergens; antiinflammatory agents; enzyme inhibitors | PFIZER INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0409484-A2 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER INC. (US) | 1991-01-23 | — | — | EP | disclosed |