Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383619 | 0.89 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| SCHEMBL9380025 | 0.89 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| SCHEMBL9380973 | 0.84 | ADRA2A (0.54) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| SCHEMBL9377847 | 0.83 | KDM4E (0.41) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| Hydrochloric Acid SCHEMBL9383454 | 0.82 | KDM4E (0.41) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| SCHEMBL9382732 | 0.75 | ADRA2A (0.43) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL9379766 | 0.74 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| SCHEMBL9378802 | 0.74 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| SCHEMBL9379803 | 0.74 | KDM4E (0.37) | ALDH1A1KDM4EHSD17B10POLBALOX15 | |
| SCHEMBL10467044 | 0.73 | ADRA2A (0.44) | ALDH1A1ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344982-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | claimed |