Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379140 | 0.88 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9379766 | 0.86 | KDM4E (0.38) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9379803 | 0.85 | KDM4E (0.37) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9380692 | 0.85 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9380696 | 0.84 | ALDH1A1 (0.38) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8926441 | 0.82 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9380937 | 0.81 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10466674 | 0.80 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9383619 | 0.80 | ALDH1A1 (0.35) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9380025 | 0.80 | KDM4E (0.35) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344982-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | claimed |