SCHEMBL9380733

SCHEMBL9380733

CCCC1(CCC)CCN(NCCCCc2ccncc2N)C1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC1 P19801 2/20 0.32
AOC3 Q16853 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9379723 0.85 AOC1 (0.35) AOC1AOC3
SCHEMBL9380737 0.74
SCHEMBL9381933 0.69 BUB1 (0.35)
SCHEMBL294034 0.69 AOC1 (0.55) AOC1AOC3
SCHEMBL5750088 0.68 AOC1 (0.53) AOC1AOC3
SCHEMBL5749554 0.68 AOC1 (0.53) AOC1AOC3
SCHEMBL5744881 0.68 AOC1 (0.53) AOC1AOC3
SCHEMBL9377517 0.67 EPHX1 (0.31)
SCHEMBL9380728 0.67 CYP19A1 (0.30)
Ammonia Solution, Strong SCHEMBL28661009 0.66 AOC1 (0.52) AOC1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413191-B1 1-(Pyridinylamino)-2-pyrrolidinones, a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1994-07-27 EP disclosed
EP-0413191-A1 1-(Pyridinylamino)-2-pyrrolidinones, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-02-20 EP disclosed
US-4994472-A Cognition activators HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-02-19 US disclosed