Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379716 | 0.88 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL9381321 | 0.78 | MAPT (0.32) | CYP19A1 | |
| SCHEMBL9381929 | 0.69 | BCHE (0.41) | — | |
| SCHEMBL9377512 | 0.67 | SLC6A2 (0.34) | — | |
| SCHEMBL9380733 | 0.67 | AOC1 (0.32) | — | |
| SCHEMBL26056119 | 0.67 | AOC1 (0.38) | CYP19A1 | |
| SCHEMBL8872029 | 0.65 | SLC6A2 (0.33) | — | |
| SCHEMBL9380737 | 0.65 | — | — | |
| SCHEMBL9206194 | 0.65 | SLC6A2 (0.34) | — | |
| SCHEMBL14216406 | 0.59 | AOC1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413191-B1 | 1-(Pyridinylamino)-2-pyrrolidinones, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1994-07-27 | — | — | EP | disclosed |
| EP-0413191-A1 | 1-(Pyridinylamino)-2-pyrrolidinones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4994472-A | Cognition activators | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-02-19 | — | — | US | disclosed |