Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385466 | 0.85 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4NOS3 | |
| SCHEMBL9385644 | 0.85 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4NOS3 | |
| SCHEMBL9387281 | 0.81 | CHRM2 (0.33) | CHRM2CHRM4CHRM5 | |
| SCHEMBL9381443 | 0.75 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL9381793 | 0.75 | ACHE (0.40) | — | |
| SCHEMBL9385827 | 0.74 | — | — | |
| SCHEMBL9386685 | 0.72 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL9380472 | 0.72 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL8969704 | 0.71 | HTR2C (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL9379498 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |