Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458685 | 0.85 | ALOX5 (0.33) | GRIN2BALOX5 | |
| SCHEMBL9380130 | 0.85 | ALOX5 (0.33) | GRIN2BALOX5 | |
| SCHEMBL9458222 | 0.84 | ALOX5 (0.36) | GRIN2BALOX5 | |
| SCHEMBL9275422 | 0.84 | LMNA (0.40) | ALOX5 | |
| SCHEMBL9275418 | 0.84 | LMNA (0.40) | ALOX5 | |
| SCHEMBL9380491 | 0.83 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL9380020 | 0.83 | CHRNA1 (0.30) | — | |
| SCHEMBL9272742 | 0.82 | POLB (0.30) | — | |
| SCHEMBL9272749 | 0.82 | POLB (0.30) | — | |
| SCHEMBL9272744 | 0.82 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409413-B1 | Diaryl ether heterocycles | ICI PLC (GB) | 1994-08-03 | — | — | EP | disclosed |
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |