Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380130 | 1.00 | ALOX5 (0.33) | ALOX5GRIN2BHSD11B1P4HB | |
| SCHEMBL9384084 | 0.86 | ALOX5 (0.33) | ALOX5GRIN2BHSD11B1 | |
| SCHEMBL9382242 | 0.86 | ALOX5 (0.33) | ALOX5GRIN2BHSD11B1 | |
| SCHEMBL9380947 | 0.85 | GRIN2B (0.32) | ALOX5GRIN2B | |
| SCHEMBL9458197 | 0.84 | SLC6A4 (0.35) | ALOX5 | |
| SCHEMBL9270822 | 0.83 | HPGD (0.44) | ALOX5 | |
| SCHEMBL9270825 | 0.83 | HPGD (0.44) | ALOX5 | |
| SCHEMBL9382942 | 0.83 | HSD11B1 (0.34) | ALOX5HSD11B1 | |
| SCHEMBL9380138 | 0.83 | HSD11B1 (0.34) | ALOX5HSD11B1 | |
| SCHEMBL9269820 | 0.82 | POLB (0.32) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |