Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380160 | 0.82 | ACHE (0.38) | ACHESMN1; SMN2 | |
| SCHEMBL9381896 | 0.79 | KMT2A (0.35) | ALDH1A1DPP4MEN1PSMD14ALPG | |
| SCHEMBL9383035 | 0.79 | KLK7 (0.36) | ALDH1A1MEN1PSMD14ALPGKMT2A | |
| SCHEMBL9380132 | 0.77 | ACHE (0.39) | ALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL9380278 | 0.77 | ACHE (0.40) | ACHE | |
| SCHEMBL9379110 | 0.75 | ACHE (0.39) | ALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL9380948 | 0.75 | ACHE (0.39) | ACHESMN1; SMN2LMNA | |
| SCHEMBL9381591 | 0.75 | ACHE (0.39) | ACHESMN1; SMN2 | |
| SCHEMBL9380862 | 0.73 | ACHE (0.47) | ALDH1A1ACHEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8969158 | 0.69 | ACHE (0.57) | ALDH1A1ACHEMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |