Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381591 | 0.84 | ACHE (0.39) | ACHEKLK7SMN1; SMN2MAPK1 | |
| SCHEMBL9379110 | 0.84 | ACHE (0.39) | ACHEHPGDKLK7SMN1; SMN2MAPK1 | |
| SCHEMBL9380132 | 0.84 | ACHE (0.39) | ACHEKLK7SMN1; SMN2 | |
| SCHEMBL9380862 | 0.80 | ACHE (0.47) | ACHEKLK7SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9380160 | 0.78 | ACHE (0.38) | ACHEKLK7SMN1; SMN2MAPK1 | |
| SCHEMBL9380245 | 0.78 | ACHE (0.33) | ACHEHPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL9380278 | 0.76 | ACHE (0.40) | ACHEKLK7 | |
| SCHEMBL9380958 | 0.75 | ALDH1A1 (0.37) | ACHESMN1; SMN2LMNA | |
| SCHEMBL9379522 | 0.74 | ACHE (0.44) | ACHEKLK7LMNA | |
| SCHEMBL9381904 | 0.73 | ACHE (0.51) | ACHEHPGDKLK7SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |