Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 10/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388115 | 0.86 | AURKA (0.42) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL8542072 | 0.84 | AURKA (0.53) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL12340644 | 0.84 | TP53 (0.39) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL9387280 | 0.83 | HTT (0.66) | AURKAHTTAPPEGFRLMNA | |
| SCHEMBL9303626 | 0.82 | PLAAT3 (0.48) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL8543977 | 0.81 | HTT (0.64) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL8546280 | 0.81 | GALR3 (0.51) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL12340671 | 0.81 | AURKA (0.44) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL8546996 | 0.81 | AURKA (0.48) | AURKARPS6KB1HTTAPPEGFR | |
| SCHEMBL8547776 | 0.80 | HTT (0.54) | AURKARPS6KB1HTTAPPEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556375-A4 | NEMATICIDAL METHOD | DOWELANCO (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0556375-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-08-25 | — | — | EP | claimed |
| WO-1993004583-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-03-18 | — | — | WO | claimed |
| EP-0556375-A4 | NEMATICIDAL METHOD | DOWELANCO (US) | 1994-05-18 | — | — | EP | disclosed |
| EP-0556375-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-08-25 | — | — | EP | disclosed |
| WO-1993004583-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |