Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 11/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 10/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382403 | 0.86 | AURKA (0.51) | AURKARPS6KB1AURKBHTTAPP | |
| SCHEMBL9303626 | 0.81 | PLAAT3 (0.48) | AURKARPS6KB1AURKBHTTAPP | |
| SCHEMBL9388070 | 0.81 | L3MBTL1 (0.36) | AURKARPS6KB1AURKBMAPK1LMNA | |
| SCHEMBL12788978 | 0.78 | L3MBTL1 (0.36) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL8546216 | 0.77 | AURKA (0.55) | AURKARPS6KB1AURKBHTTAPP | |
| SCHEMBL13456925 | 0.77 | AURKA (0.48) | AURKARPS6KB1HTTAPPMAPK1 | |
| SCHEMBL8546280 | 0.76 | GALR3 (0.51) | AURKARPS6KB1HTTAPPMAPK1 | |
| SCHEMBL8543977 | 0.76 | HTT (0.64) | AURKARPS6KB1HTTAPPMAPK1 | |
| SCHEMBL2180011 | 0.76 | LMNA (0.36) | AURKAAURKBHTTMAPK1LMNA | |
| SCHEMBL8546996 | 0.76 | AURKA (0.48) | AURKARPS6KB1AURKBHTTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004527-A1 | PYRIDYLETHOXY-, PYRIDYLETHYLAMINO-, AND PYRIDYLPROPYL-DERIVATIVES OF QUINOLINE AND QUINAZOLINE AS INSECTICIDES AND FUNGICIDES | DOWELANCO (US) | 1994-03-03 | — | — | WO | claimed |
| WO-1994004527-A1 | PYRIDYLETHOXY-, PYRIDYLETHYLAMINO-, AND PYRIDYLPROPYL-DERIVATIVES OF QUINOLINE AND QUINAZOLINE AS INSECTICIDES AND FUNGICIDES | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1994004527-A1 | PYRIDYLETHOXY-, PYRIDYLETHYLAMINO-, AND PYRIDYLPROPYL-DERIVATIVES OF QUINOLINE AND QUINAZOLINE AS INSECTICIDES AND FUNGICIDES | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |