Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382599 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4ERAB9ACTSLL3MBTL1 | |
| SCHEMBL9383807 | 0.84 | CTSS (0.58) | CTSL | |
| SCHEMBL9383811 | 0.84 | CTSS (0.58) | CTSL | |
| SCHEMBL4763256 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4ECTSLL3MBTL1FPR2 | |
| SCHEMBL4763260 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4ECTSLL3MBTL1FPR2 | |
| SCHEMBL34468338 | 0.76 | EPHX2 (0.62) | ALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL15055182 | 0.76 | EPHX2 (0.62) | ALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL30718482 | 0.76 | EPHX2 (0.62) | ALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL27002666 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4ERAB9ACTSLL3MBTL1 | |
| SCHEMBL27125782 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4ERAB9ACTSLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304087-B1 | Quinolone and naphthyridine antibacterial agents containing an alpha-amino acid in the side chain of the 7-substituent | WARNER LAMBERT CO (US) | 1994-03-30 | — | — | EP | disclosed |
| US-4851418-A | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent | WARNER-LAMBERT COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0304087-A2 | Quinolone and naphthyridine antibacterial agents containing an alpha-amino acid in the side chain of the 7-substituent | WARNER-LAMBERT COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |