Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19579755 | 0.87 | MRGPRX4 (0.49) | KDM4EMRGPRX4 | |
| SCHEMBL9378776 | 0.80 | TDP1 (0.54) | PTGDR2KDM4E | |
| SCHEMBL9378807 | 0.78 | ALOX15 (0.66) | PTGDR2KDM4E | |
| SCHEMBL9379551 | 0.78 | KCNH2 (0.55) | PTGDR2KDM4E | |
| SCHEMBL28496945 | 0.76 | KDM4E (0.49) | KDM4E | |
| SCHEMBL30120650 | 0.76 | KDM4E (0.49) | KDM4E | |
| SCHEMBL9379799 | 0.76 | PKM (0.50) | PTGDR2KDM4EAKR1B1 | |
| SCHEMBL9379478 | 0.76 | KDM4E (0.46) | KDM4E | |
| SCHEMBL19579739 | 0.76 | HTT (0.50) | KDM4EMRGPRX4 | |
| SCHEMBL28666661 | 0.74 | PTGDR2 (0.53) | PTGDR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398283-B1 | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1994-11-02 | — | — | EP | disclosed |